| Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI g | DPI g | Num. diseases |
|---|---|---|---|---|---|---|---|
| VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | 7 | |
| VAPB | O95292 | VAMP associated protein B and C | Transporter | 0.58 | 0.666 | 0.423 | 3 |
| UNC13A | Q9UPW8 | unc-13 homolog A | 1.00 | 0.705 | 0.423 | 1 | |
| UBQLN2 | Q9UHD9 | ubiquilin 2 | 0.85 | 0.656 | 0.462 | 1 | |
| TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | 5 | |
| TBK1 | Q9UHD2 | TANK binding kinase 1 | Kinase | 7.5E-02 | 0.513 | 0.846 | 4 |
| TARDBP | Q13148 | TAR DNA binding protein | 0.99 | 0.493 | 0.808 | 2 | |
| TAF15 | Q92804 | TATA-box binding protein associated factor 15 | Nucleic acid binding | 0.17 | 0.626 | 0.500 | 2 |
| SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | 5 | |
| SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 | 1 |
| PRPH | P41219 | peripherin | 4.8E-14 | 0.623 | 0.462 | 1 | |
| PPARGC1A | Q9UBK2 | PPARG coactivator 1 alpha | Transcription factor | 1.00 | 0.453 | 0.885 | 1 |
| PON3 | Q15166 | paraoxonase 3 | 2.1E-07 | 0.663 | 0.692 | 1 | |
| PON2 | Q15165 | paraoxonase 2 | 5.4E-05 | 0.566 | 0.808 | 1 | |
| PON1 | P27169 | paraoxonase 1 | 9.8E-11 | 0.409 | 0.885 | 1 | |
| PFN1 | P07737 | profilin 1 | 0.73 | 0.565 | 0.769 | 1 | |
| OPTN | Q96CV9 | optineurin | 5.9E-18 | 0.548 | 0.808 | 1 | |
| NEK1 | Q96PY6 | NIMA related kinase 1 | Kinase | 1.9E-25 | 0.575 | 0.769 | 4 |
| NEFH | P12036 | neurofilament heavy | 2.7E-12 | 0.588 | 0.769 | 1 | |
| MATR3 | P43243 | matrin 3 | 1.00 | 0.631 | 0.538 | 1 | |
| HNRNPA1 | P09651 | heterogeneous nuclear ribonucleoprotein A1 | 1.00 | 0.529 | 0.885 | 2 | |
| GLT8D1 | Q68CQ7 | glycosyltransferase 8 domain containing 1 | 1.1E-08 | 0.711 | 0.462 | 1 | |
| GLE1 | Q53GS7 | GLE1 RNA export mediator | Transporter | 2.1E-10 | 0.628 | 0.577 | 3 |
| FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 | 5 |